Bilateral Anterior Capsulotomy, Cingulotomy, and Nucleus Accumbens Stereotactic Ablation in Obsessive-Compulsive Disorder Patients Presenting with Agitation and Irritability

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511837235251

Enrollment

Registered

2025-11-06

Start date

2025-11-15

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases

Interventions

Bilateral Anterior Capsulotomy and Cingulotomy and Nucleus Accumbens Stereotactic Ablation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Age from 18 to 65 years. • Both sexes. • Patients fulfilled the current Diagnostic and Statistical Manual (DSM-IV) criteria for obsessive compulsive disorder (OCD). • Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score = 24. • Prominent agitation and irritability.

Exclusion criteria

Exclusion criteria: • Organic brain syndrome. • Abuse of alcohol, sedatives or illicit drugs. • Presence of any delusional disorders. • Complicating current axis II diagnosis from clusters A or B, or a current axis III diagnosis with brain pathology, such as moderate or marked atrophy, stroke, tumor or a history of previous neurosurgical procedures that might produce complications.

Design outcomes

Primary

Measure	Time frame
Yale Brown Obsessive Compulsive Scale (Y-BOCS)	—

Secondary

Measure	Time frame
Hamilton Scale for Depression (HAM-D);Brown Assessment of Beliefs Scale (BABS);Sheehan Disability Scale	—

Countries

Egypt

Contacts

Public ContactAhmed Taha

Assistant Professor

ahmed.taha.abdella.1980@gmail.com00201148048480

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026