Circulatory System Nutritional, Metabolic, Endocrine
Conditions
Interventions
Ticagrelor
Sponsors
Ain Shams University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Diagnosed diabetes mellitus (Type 2) • Acute coronary syndrome (STEMI or NSTEMI or Unstable angina) • Undergoing successful PCI with drug-eluting stent • Able to start dual antiplatelet therapy after PCI • Age = 18 and = 80 years • Able to provide informed consent
Exclusion criteria
Exclusion criteria: • Age 80 years • History of hemorrhagic stroke • Ischemic stroke, dementia, or CNS impairment within the past 12 months • Traumatic brain injury or brain surgery within the past 6 months • Known intracranial tumor or suspected aortic dissection • Documented bleeding disorders or platelet dysfunction • Current oral anticoagulant therapy • Severe anemia or thrombocytopenia • Severe liver disease • Mental retardation, psychiatric illness, or inability to comply with follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiovascular events (MACE): composite of cardiac death, myocardial infarction, ischemic stroke, and repeat PCI | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding events (classified as trivial, mild, moderate, severe, or life-threatening);Hemoglobin level (g/dl);Platelet count (×10³/µL);Recurrent chest pain or angina symptoms | — |
Countries
Egypt
Contacts
Public ContactAhmed Ali
Cardiology Department
Outcome results
None listed