Combined Femoral and Sciatic Nerve Blocks versus Local Anesthesia with Dexmedetomidine Sedation for Endovascular interventions in chronic lower limb threatening ischemia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511788882617

Enrollment

Registered

2025-11-07

Start date

2025-11-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Combined Femoral and Sciatic Nerve Block is performed using an ultrasound guided nerve block

Local Anesthesia plus Dexmedetomidine Sedation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age more than 45years ASA II or III , Undergoing endovascular interventions in chronic lower limb threatening ischemia On dual antiplatelet therapy (aspirin + clopidogrel/ticagrelor)

Exclusion criteria

Exclusion criteria: Allergy to local anesthetics, dexmedetomidine, or any study medication. Local infection at the site of planned nerve block. Coagulopathy: INR > 1.5, platelet count < 75,000/mm³, or additional anticoagulation. Severe peripheral neuropathy or pre-existing motor/sensory deficits in the affected limb. Inability to communicate pain or consent Severe bradycardia (HR < 50 bpm), heart block, or unstable cardiovascular status

Design outcomes

Primary

Measure	Time frame
Maximum intraoperative pain score	—

Secondary

Measure	Time frame
Time to first postoperative analgesic request	—

Countries

Egypt

Contacts

Public ContactManar Ahmed Mahmoud

residant doctor at Anaesthesia ICU and pain management Assiut university

miarahmed777@gmail.com+201142005998

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026