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Ceftriaxone alone versus Ceftriaxone with Metronidazole in preventing postoperative infections following caesarean section in Yenagoa: A randomised controlled trial.

Ceftriaxone alone versus Ceftriaxone with Metronidazole in preventing postoperative infections following caesarean section in Yenagoa: A randomised controlled trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202511775331231
Enrollment
118
Registered
2025-11-14
Start date
2025-02-25
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nil

Interventions

Ceftriaxone 1 g IV and Metronidazole 500 mg IV at induction of anaesthesia
Ceftriaxone Group Participants receive Ceftriaxone 1g IV at induction of anaesthesia.

Sponsors

AGBAGORO OGHENETEGA JESSE
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria for the study were women 1. Aged 15 to 49 years who were undergoing either elective or emergency caesarean sections 2. Who had a singleton pregnancy, 3. who do not have known allergies to Ceftriaxones or Metronidazole. 4. Booked patients

Exclusion criteria

Exclusion criteria: Exclusion criteria included women 1. with history of complications from previous caesarean sections, 2. those presenting with an active infection at the time of surgery, 3. individuals with known immunocompromised conditions such as HIV or undergoing chemotherapy, and those with pre-existing chronic conditions like diabetes or hypertension. 4. Also, patients having anaemia, BMI >30kg/m2, preoperative fever, antibiotics use within 1 week, allergic to ceftriaxone or metronidazole, 5.patients with ruptured membranes with evidence of infection and chorioamnionitis were excluded.

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is the incidence of postoperative infections, such as surgical site infections and endometritis, within 30 days after surgery. Secondary outcomes include the length of hospital stay, incidence of adverse drug reactions, and the cost of treatment, both direct and indirect costs.

Secondary

MeasureTime frame
Secondary outcomes include the length of hospital stay, incidence of adverse drug reactions, and the cost of treatment, both direct and indirect costs.

Countries

Nigeria

Contacts

Public ContactSAMUEL AIGERE

CONSULTANT OBGYN SPECIALIST

draigere@yahoo.com+2347035410776

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026