Anaesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a.Female, age 19–45years. c. Elective laparoscopic procedure under general anaesthesia with endotracheal intubation. d. Expected surgical duration = 30 minutes. e.Ability to consent and complete questionnaires.
Exclusion criteria
Exclusion criteria: Pregnancy or lactation. BMI = 40 kg/m²; severe cardiopulmonary disease; hepatic/renal failure. History of malignant hyperthermia or contraindication to study drugs. Known allergy to propofol, sevoflurane,or desflurane.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post operative nausea and vomiting (0–24 h): Any episode of nausea (NRS = 4/10 or requiring treatment) and/or vomiting/retching recorded; need for rescue antiemetic. PONV Scoring System 1. Nausea (assessed by NRS 0–10) 0 ? No nausea 1–3 ? Mild nausea 4–6 ? Moderate nausea 7–10 ? Severe nausea 2. Vomiting Episodes 0 ? No vomiting 1 ? 1 episode 2 ? 2 episodes 3 ? =3 episodes | — |
Secondary
| Measure | Time frame |
|---|---|
| Time from end of surgery to extubation | — |
Countries
Egypt
Contacts
Resident of Anesthesia Intensive Care and Pain Management Faculty of medicine Assiut University