Extubation failure of mechanical ventilation

Efficacy of high flow nasal cannula versus non invasive mechanical ventilation in prevention of extubation failure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511679241574

Enrollment

Registered

2025-11-20

Start date

2025-11-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics

Interventions

Non invasive mechanical ventilation

High flow nasal cannula group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1- Patient aged more than 1month and less than 18years old. 2- Patient who will be intubated with respiratory failure due to respiratory cause . 3- Patient on MV extubated and weaned on either NIV or HFNC

Exclusion criteria

Exclusion criteria: Patient who has a tracheostomy, Patient who underwent unplanned extubation. 2- Patient who had history of prematurity or associated with bronchopulmonary dysplasia. 3- Patient in need of oxygen therapy due to chronic pulmonary disease 4- Patient with co-morbid conditions that affect weaning procedures e,g(cardiorespiratory arrest, hemodynamic instablility, GCS < than 10, upper GIT bleeding, vocal cord palsy, Cases of postoperative congenital heart disease).

Design outcomes

Primary

Measure	Time frame
Prevention of extubation failure in pediatric intensive care unit	—

Secondary

Measure	Time frame
Decrease morbidity and mortality	—

Countries

Egypt

Contacts

Public ContactSafwat Abdelaziz

Professor

alaa_safwat@aun.edu.eg+201003918080

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026