Echocardiographic assessment of Left atrium strain in patients with cardiac implanted devices with atrial high rate episodes.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511663104194

Enrollment

130

Registered

2025-11-20

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiology

Interventions

AHRE group

Non AHRE group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Patients = 18 years with dual-chamber pacemakers, CRT or ICDs with atrial leads. • Device capable of AHRE detection. • Sinus rhythm at baseline.

Exclusion criteria

Exclusion criteria: • Permanent or diagnosed paroxysmal AF (by documented 12 lead surface ECG) or atrial flutter. • History of prior catheter ablation. • Severe valvular heart disease or Cardiac valve prosthesis. • Poor echocardiographic window

Design outcomes

Primary

Measure	Time frame
The primary endpoint: •To study the association between AHRE detected on CIED patients and LA strain parameters	—

Secondary

Measure	Time frame
The secondary effectiveness endpoints: 1. To detect association between atrial mechanical dysfunction with AHRE burden. 2. To assess the additive value of advanced imaging (STE) over conventional echocardiographic parameters. 3. To assess association between AHRE and thromboembolic events including cerebrovascular stroke, limb ischemia and other embolic manifestations. 4. To assess association between LA dysfunction and thromboembolic events including cerebrovascular stroke, limb ischemia and other embolic manifestations.	—

Measure

Time frame

The secondary effectiveness endpoints: 1. To detect association between atrial mechanical dysfunction with AHRE burden. 2. To assess the additive value of advanced imaging (STE) over conventional echocardiographic parameters. 3. To assess association between AHRE and thromboembolic events including cerebrovascular stroke, limb ischemia and other embolic manifestations. 4. To assess association between LA dysfunction and thromboembolic events including cerebrovascular stroke, limb ischemia and other embolic manifestations.

—

Countries

Egypt

Contacts

Public ContactMohamed Aboelhassan Abdelrady

Physician

mabolhassan10@gmail.com+201115825387

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026