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Platelet-Rich Plasma (PRP) in comparison to silver nitrate application for the management of cervical ectopy

Topical versus intra-lesion injection of Platelet-Rich Plasma (PRP) in comparison to silver nitrate application for the management of cervical ectopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202511567614411
Enrollment
144
Registered
2025-11-20
Start date
2025-10-18
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical ectopy

Interventions

Group A with PRP will be applied topically.
Group B with PRP injected .
group C with silver nitrate

Sponsors

Sara Elsayed Mohammed PhD student
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: *Married sexually active females in the reproductive age (20-45) years. *Women with cervical ectopy symptomatic with vaginal discharge, postcoital bleeding, pelvic pain, recurrent cervicitis. *Women with cervical ectopy diagnosed by examination and colposcope and failed to respond to antibiotic treatment *Pap smear shows only inflammatory changes.

Exclusion criteria

Exclusion criteria: Subjects who did not provide consent. *Subjects having dysplastic or neoplastic cells on cervical smear test and colposcopy (CIN I - CIN II -CIN III or cervical cancer) *Subjects having other gynecologic disorders including uterus prolapse *Subjects who are pregnant or breast feeding or post-menopausal or on hormonal contraception. *Subjects who have high numbers of leucocytes (usually >30 per high power field) in the vaginal smear or have an active infection confirmed by culture and sensitivity. Subjects having platelet dysfunction (thrombocytopenia) or other hematological disorders *Subjects unwilling to return for follow-up visits *Subjects with associated mass lesions in the cervix. * Subjects who are immunocompromised (Diabetes mellitus – Systemic lupus erythematous)

Design outcomes

Primary

MeasureTime frame
To show the efficacy of topical versus intra-lesion injection of Platelet- rich plasma (PRP) in comparison to the application silver nitrate for the management of cervical ectopy.

Secondary

MeasureTime frame
The possible complications of each management technique.

Countries

Egypt

Contacts

Public ContactMohamed Adel

Suez Canal University

prince.ma939@yahoo.com00201020210024

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026