Video Assisted Thoracoscopic Surgery versus Thoracostomy Tube for Drainage and Pleurodesis in the Management of Pleural Effusion in Malignancy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511559490504

Enrollment

100

Registered

2025-11-24

Start date

2024-06-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Respiratory

Interventions

Video assisted thoracoscopic surgery

Thoracostomy tube pleurodesis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eligible patients were adults with cytologically or histologically confirmed pleural effusion in the setting of malignancy who were capable of providing informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria included pleural effusion from non-malignant causes (e.g., heart failure, pneumonia), prior thoracic surgery on the same side, coagulopathy or active bleeding disorder, uncontrolled systemic infection, or refusal to participate.

Design outcomes

Primary

Measure	Time frame
Successful pleurodesis at 30 days, defined as a complete response (CR), no radiographic evidence of fluid reaccumulation compared with the immediate post-procedure baseline. All other cases were classified as failures.	—

Secondary

Measure	Time frame
Postoperative pain, complications, ICU admission, and length of hospital stay	—

Countries

Egypt

Contacts

Public ContactAhmed Soliman

Mansoura University

ahmedsolimann9090@gmail.com00201550071055

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026