Laparoscopic Management of Pyogenic Liver Abscess

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511527285878

Enrollment

Registered

2025-11-28

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pyogenic liver abscess Surgery

Interventions

Laparoscopic Drainage of Liver Abscess

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adults =18 years Radiologically confirmed liver abscess (US/CT/MRI) Abscess =3 cm, symptomatic, or not responding to antibiotics Solitary or multiple abscesses accessible laparoscopically Failed or contraindicated percutaneous drainage, or primary laparoscopic drainage offered

Exclusion criteria

Exclusion criteria: Uncorrected coagulopathy (INR >1.5 or platelets <50×10?/L) Hemodynamic instability or septic shock unresponsive to resuscitation Diffuse peritonitis requiring immediate open surgery Extensive hepatic necrosis or malignancy precluding laparoscopic approach Severe cardiopulmonary disease making pneumoperitoneum unsafe

Design outcomes

Primary

Measure	Time frame
Complete clinical and radiological resolution of the liver abscess within 90 days after laparoscopic intervention, without need for further drainage.	—

Secondary

Measure	Time frame
Technical success of laparoscopic drainage, major complication rate within 30 days, abscess recurrence within 6 months, need for additional intervention (repeat or open drainage), length of hospital stay, time to clinical improvement (fever/CRP/WBC normalization), operative time and blood loss, postoperative pain and analgesic use.	—

Countries

Egypt

Contacts

Public ContactSalah Ibrahim

Assiut University

MISs.ibrahim@aun.edu.eg+201061616104

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026