Bacterial Vagionosis Pregnancy and Childbirth Urological and Genital Diseases Fertility-female
Conditions
Interventions
Sponsors
Faculty of Medicine. Ain Shams University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: - Women aged = 18 years with a clinical diagnosis and laboratory diagnosis as (cervical smear & high vaginal swab) of bacterial vaginosis. - Diagnosed with Bacterial vaginosis the Amsel scoring system which requires 3 criteria of 4 criteria for diagnosis: - The presence of homogeneous, thin, greyish white vaginal discharge. - Vaginal pH over 4.5. - Positive whiff-amine test (the presence of a fishy odor following addition of KOH to the vaginal sample). - More than 20% clue cells/high power field on a wet mount of vaginal secretions. - This examinations were done at Ain shams Maternity laboratory hospitals
Exclusion criteria
Exclusion criteria: Other types of infections based on history and clinical examination as candida vaginitis (itching with cottage cheese whitish discharge, Trichomonas vaginalis (with yellowish green offensive discharge) and any sexually transmitted disease (STDs) as gonorrhea(watery creamy greenish discharge, pain on micturation)syphilis(appearance of shung-kur ulcer, painless sore), chlamydia(abnormal discharge from vagina, burning sensation on peeing, abnormal discharge from penis) or genital herpes (tingling, burning, itching around genitals on both parteners). - Pregnant and lactating females - Any contraindication or hypersensitivity to metronidazole use - Use of other antibiotics or systemic antifungal agents within the previous 2 weeks or planned use within 2 weeks - Use of topical vaginal antibiotics, antifungals or acidifying products recently or planned within 2 weeks - Atrophic vaginitis - Using IUD as contraceptive method because IUD is a risk factor for infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of both medications (reliving symptoms of Bacterial Vaginosis as discharge & odour) and microbiological detection in the laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects as local vulvovaginal irritation, diarrhea etc as In case of persistent infection the medication dose will be changed investigation the case of resistance | — |
Countries
Egypt
Contacts
Public ContactLaila Aly Farid
Professor of Obstetrics and Gynecology. Faculty of Medicine. Ain Shams University
Outcome results
None listed