Anaesthesia
Conditions
Interventions
20 ml of normal saline before standardized general anesthesia for ACDF
group D. intravenous dexamedetomidine
Sponsors
anesthesia department. facylty of medicine meniudia university egypt
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Patients aged between 18-60 years’ old • ASA physical status I- II, of either sex • Elective anterior cervical discectomy and fusion under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Pre-existing bradycardia [heart rate (HR) below 50/min]. 2. Hypotension (systolic arterial pressure 140/90) 4. Planned elective postoperative ventilation; poor respiratory reserve and poor cough reflex. 5. Presence of cardiac, renal, hepatic, neurological and respiratory dysfunction; cognitive impairment. 6. Known allergy to a2 -agonists. 7. Use of ß-blockers, digoxin, , or a2 -agonists.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time to emergence from general anesthesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| intraoperative parameters (consumption of propofol, isoflurane, and fentanyl), the quality of emergence (assessed by coughing/bucking severity and sedation scores), postoperative pain profiles (VAS scores and analgesic requirements), the incidence of nausea and vomiting (PONV), time to meet PACU discharge criteria, and the overall rate of adverse events. | — |
Countries
Egypt
Contacts
Public Contactmohamed soliman
lecturer of anesthesiology
Outcome results
None listed