Oral labetalol versus oral alpha methyl dopa for managing preeclampsia at the University of Maiduguri Teaching Hospital: A randomized controlled study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202510836146767

Enrollment

108

Registered

2025-10-22

Start date

2025-10-06

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia

Interventions

Labetalol

Alpha methyl dopa

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Gestational age of 28weeks and above Live singleton pregnancy Both primigravida and multigravida Age group 16-40 years

Exclusion criteria

Exclusion criteria: Contraindication or known allergy to labetalol or methyldopa Women that present with eclampsia Women with chronic hypertension, cardiac failure, asthma, diabetes mellitus Women that present in labour Women with confirmed IUFD, suspected fetal compromise.

Design outcomes

Primary

Measure	Time frame
The primary outcome will be change in both mean systolic and mean diastolic blood pressure measurements achieved after a period of 48hours on the antihypertensive.	—

Secondary

Measure	Time frame
The secondary outcomes will be side effect of the drug effects on the mother (e.g. Dizziness, headache, nausea, vomiting, depression etc.), need for additional antihypertensive, maternal complication such as eclampsia, abruption etc, mode of delivery (vaginal or abdominal), onset of labour (spontaneous or induced), terminating pregnancy on account of severe preeclampsia and neonatal outcomes (alive, Apgar scores, admission into special care baby, still born)	—

Measure

Time frame

The secondary outcomes will be side effect of the drug effects on the mother (e.g. Dizziness, headache, nausea, vomiting, depression etc.), need for additional antihypertensive, maternal complication such as eclampsia, abruption etc, mode of delivery (vaginal or abdominal), onset of labour (spontaneous or induced), terminating pregnancy on account of severe preeclampsia and neonatal outcomes (alive, Apgar scores, admission into special care baby, still born)

—

Countries

Nigeria

Contacts

Public ContactAbubakar Kullima Ali

Senior lecturer and consultant Obstetrics and Gynaecology.

kullima@yahoo.com+2348036142528

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026