Digestive System Peptic Ulcer Disease
Conditions
Interventions
Ursus 1 Mixture
Sponsors
Magdalene Oti
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Males and females • Adult ages 18 years and above • Patients with the following presentations: o Epigatric pain o Heart burn o Nausea and vomiting o Abdominal discomfort o Indigestion o Gastritis • Presence of H.pylori on laboratory investigation • No history of ingestion of any antibiotics, NSAIDS and anti-ulcer product within the past 30 days • Patients able and willing to come back for follow up • Easy access to the health facility
Exclusion criteria
Exclusion criteria: • Age less than 18 years • Complications of peptic ulcer including haemorrhage • Chronic ingestion of NSAIDs • Disturbed Gastrointestinal physiology (vagotomy, gastric surgery, Zollinger-Ellison syndrome) • Breastfeeding or pregnant females • Haemoglobin below 8g/dl • Individuals on other medication for PUD. (Eg. Antibiotics, proton pump inhibitor, etc) • Patients with concomitant diseases e.g. Diabetes, hypertension, liver and/or renal disease(s) • Patients on using other medications that may interact with the study (e.g., Warfarin, anti- epileptics) • Presence of clinically significant abnormal laboratory results during screening • Use of any recreational drugs or having a history of drug dependence • Inability to come for stipulated follow-up visits
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of effectiveness based on improvement of frequency of occurrence of symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Clearance of H.pylori | — |
Countries
Ghana
Contacts
Public ContactJohn Appiahpoku
Kwame Nkrumah University of Science and Technology
Outcome results
None listed