Excimer Laser 308nm versus Fractional CO2 Laser plus Topical Methotrexate in Chronic Plaque Psoriasis

Excimer Laser versus Fractional CO2 Laser plus Topical Methotrexate 1% in Chronic Plaque Psoriasis: Randomized Comparative Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202510680658151

Enrollment

124

Registered

2025-10-28

Start date

2024-06-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin and Connective Tissue Diseases

Interventions

Excimer laser

Fractional carbon dioxide laser with topical methotrexate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients aged more than 18 years. - Both sexes. - Patients with a confirmed diagnosis of chronic plaque psoriasis.

Exclusion criteria

Exclusion criteria: - Having any treatment for psoriasis 6 months prior to the examination. - Pregnancy. - History of allergy to any drug. - Having any systemic diseases.

Design outcomes

Primary

Measure	Time frame
Incidence of improvement	—

Secondary

Measure	Time frame
Incidence of complications;Degree of patients satisfaction ;Clinical assessment Erythema, Scaling and Infiltration (ESI) Score System	—

Countries

Egypt

Contacts

Public ContactHeba AbdelAzeem

Lecturer

Heba_84@live.com00201013481678

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026