Digestive System
Conditions
Interventions
Omeprazole based high dose amoxicillin DT
Vonoprazan based high dose amoxicillin DT
Sponsors
Al Azhar University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients diagnosed with H. pylori infection age of 18 and above.
Exclusion criteria
Exclusion criteria: patients under the age of 18, had a known allergy to any of the medications used in this medical trial, had undergone H. pylori eradication therapy, had taken any of the following medications within the past six weeks: PPI, antibiotics, non-steroidal anti-inflammatory drugs, and anticoagulant treatment; Recent gastric surgery, gastrointestinal cancer, active gastrointestinal bleeding, women who are pregnant or nursing; patients with acute renal or liver disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rate of H.pylori in each group | — |
Secondary
| Measure | Time frame |
|---|---|
| evaluate safety of used regimens by incidence of adverse reactions and evaluate improvement of symptoms especially dyspepsia and epigastric pain. | — |
Countries
Egypt
Contacts
Public ContactAbdelwahab Ali
Professor of Hepatology Gastroenterology and Infectious disease
Outcome results
None listed