Evaluation Of The Effect Of Synthetic Exosomes On Periorbital Rejuvenation: A Single-Arm Clinical Trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202510463370770

Enrollment

Registered

2025-10-08

Start date

2025-10-15

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wrinkles, fine lines, dyschromia around eyes

Interventions

Synthetic Exosomes

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Males and Females aged between 30 to 60 Presence of fine lines to moderate periorbital wrinkles Presence of dyschromias around eyes

Exclusion criteria

Exclusion criteria: History of facial treatments (including topical agents ,laser therapy, chemical or organic peels, microneedling ,platelet-rich plasma (PRP) within past 2 months) History of botulinum toxin (Botox), dermal filler or Fat injections within the last 6 months Presence of infectious or autoimmune skin diseases Pregnant or lactating females Severe periorbital wrinkles Current or recent use (within 6 months) of oral vitamin A derivatives Diagnosed psychiatric disorders including dysmorphic disorder

Design outcomes

Primary

Measure	Time frame
Evaluation of the efficacy of synthetic exosomes in the rejuvenation of periorbital region.	—

Secondary

Measure	Time frame
Assessing the improvement of skin texture, elasticity, dyschromias and wrinkle reduction (Standarized photography, The Merz Scale and Global Aesthetic Improvement Scale)	—

Countries

Egypt

Contacts

Public ContactNourihan Elhalawany

Plastic Surgery Resident Kasr Al Ainy Hospital Cairo University

nourhan.elhalawany1994@gmail.com00201151834492

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026