Topical Prilocaine-Lidocaine Cream as an Adjunct to Pudendal Nerve Block for Pediatric Circumcision: A Randomized Controlled Trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202509887535752

Enrollment

120

Registered

2025-09-29

Start date

2025-07-10

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

pudendal nerve block with prior application of lidocaine prilocaine cream

pudendal nerve block alone

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: ASA I children over 2 years old undergoing sevoflurane anesthesia for circumcision

Exclusion criteria

Exclusion criteria: contraindications to halogenated agents contraindications to local anesthetics coagulation disorders non fasting status genital anomalies

Design outcomes

Primary

Measure	Time frame
The primary outcome was intraoperative nociception, assessed by hemodynamic and respiratory parameter variation (heart rate, respiratory rate, SpO2) and sevoflurane MAC variation	—

Secondary

Measure	Time frame
postoperative pain (FLACC scale);emergence agitation, measured with Aono's four-point scale	—

Countries

Tunisia

Contacts

Public Contactimen ennaas

military hospital of tunis

imen.naas@fmt.utm.tn+21626622590

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026