Eye Diseases
Conditions
Sponsors
Abe Adeola
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who give their consents. 2. Patients with grade 2 and 3 corneal opacity, with associated neovascularization grade 2 to 4 who present to the eye clinic of LASUTH within the period of study. 3. Age-18 years ( legal age for consent in Nigeria ) to 80 years. 4. Patients not on any anti VEGF therapy in the previous one month.
Exclusion criteria
Exclusion criteria: 1. Patients younger than 18yrs. 2. Patients with an active ocular inflammation or infection. 3. Patients with visual impairment from other causes like cataract, uncontrolled glaucoma and macular disorders. 4. Patient with no light perception in the eye for study. 5. Patient with an only eye. 6. Patients with an uncontrolled hypertension and other contraindications to bevacizumab like cardiac diseases, renal failure and gastrointestinal perforations. 7. Pregnant and lactating mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures will be: 1.The number of corneal surface segment covered by opacity using digital pictures with a specially made computer-generated pattern of segments which is to be fitted over the digital corneal photograph taken for the estimation. And 2. The number of corneal surface segments with corneal neovascularization. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures will be: 1.The best corrected visual acuity. 2.complications related to the interventions and 3.participants’ quality of life changes. | — |
Countries
Nigeria
Contacts
Public ContactSedoten Bashorun
Consultant Department of Ophthalmology LASUTH
Outcome results
None listed