The efficacy and safety of nefopam in post caesarean section pain management
Conditions
Interventions
Intravenous nefopam
Sponsors
Maria Bassey
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women aged 19 – 44years 2. Women undergoing elective or emergency Caesarean section under spinal anaesthesia 3. Singleton pregnancy at term (37-41weeks) 4. American society of Anaesthesiologist (ASA) physical status classification 1 or 11
Exclusion criteria
Exclusion criteria: 1. Known allergy or hypersensitivity to nefopam, diclofenac, paracetamol or pentazocine. 2. History of chronic pain 3. History of regular use of analgesics 4. Presence of comorbidities including renal, hepatic, cardiovascular or seizure disorders. 5. Conversion to general anaesthesia intraoperatively. 6. Patients on monoamine oxidase inhibitors (MAOIs). 7. Women with a known history of peptic ulcer disease 8. Contraindications to NSAIDs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This is a post intervention outcome. Pain intensity will be measured by using Visual Analogue Scale (VAS, 0–10). | — |
Secondary
| Measure | Time frame |
|---|---|
| This is a post intervention outcome. This outcome will seek to determine if IV nefopam reduces the frequency of the use of rescue analgesia. And secondly, to determine the incidence of side effects and assess patient satisfaction at the 24th hour using the Likert scale. | — |
Countries
Nigeria
Contacts
Public ContactOtobong Asuquo
Consultant obstetrician and gynaecologist
Outcome results
None listed