Skip to content

Impact of dexmedetomidine on optic nerve sheath diameter during abdominal aortic aneurysm repair.

Impact of dexmedetomidine on sonographic optic nerve sheath diameter during abdominal aortic aneurysm repair: A randomized controlled trial.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202509618978504
Enrollment
50
Registered
2025-09-02
Start date
2025-09-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Group C placebo infusion
Group D dexmetomedine infusion

Sponsors

mansoura university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged from 30 to 65 years old. 2. Patients had a body mass index less than 30 kg/m2. 3. Patients had conditions classified as ? and ?? according to the American Society of Anesthesiologists. 4. Patients suffered from abdominal aortic aneurysms.

Exclusion criteria

Exclusion criteria: 1. Patient’s refusal. 2. Patients who had eye diseases, central nervous system diseases, cardiovascular diseases and or diabetes. 3. Patients whose ultrasound scans or measurements failed to clearly show the structure of optic nerve sheath diameter. 4. Patients whose surgical time was less than 1 hour. 5. Patients had a history of allergy to a2 agonists.

Design outcomes

Primary

MeasureTime frame
sonographic optic nerve sheath diameter (ONSD) as a non-invasive indicator of intracranial pressure during elective abdominal aortic aneurysm (AAA) repair.

Secondary

MeasureTime frame
MAP, HR and oxygen saturation ;Postoperative complication as postoperative dizziness, nausea, vomiting headache ;The time to awakening the duration between the completion of surgery and the occurrence of eye-opening spontaneously or in response to a spoken order or according to Ricker sedation-agitation scale.

Countries

Egypt

Contacts

Public ContactMaha Younis Youssef Abdallh

assistant professor

nashaatbaraka1@gmail.com00966592308487

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026