Malaria
Conditions
Interventions
Therapeutic Efficacy Studies of 2019
Sponsors
Malaria Elimination Program Minster of Health Ethiopia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Self-reporting febrile patients (axillary temperature = 37.5°C) or with a history of fever within the past 24 hours at the time of diagnosis Volunteer to participate in the study protocol Microscopy and RDT confirmed uncomplicated P. falciparum mono-infected, 6 months or older, body weights >5kg, hemoglobin >5.0 g/dL and above, parasitemia = 500 parasites/µL, HCG negative and/or non-breastfeeding, and residence within 20 km radius of the study site (Bambasi health center) and Written informed consent or assent for those between the ages of 11 to 18 in addition to parental consent were sought.
Exclusion criteria
Exclusion criteria: microscopically mixed infection Refused to consent/assent HCG Positive and or breastfeeding Clients with known coinfection or chronic diseases Out of catchment area parasitemia < 500 parasites/µL, Anemic Underweight and Non-volunteer to participate in the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the studies are rapid parasite clearance, clinical recovery, fever clearance, and overall health improvement. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome of the studies are reduced hospitalization/severity or complications, and reduction in transmission reservoir and returning of patients into regular or economic activities. | — |
Countries
Ethiopia
Contacts
Public ContactGirma Shumie
Armauer Hansen Research Institute
Outcome results
None listed