Impact of Exercise on Selected Inflammatory and Cardiac Stress Biomarkers in Type 2 Diabetes and Its Implication for Pulmonary and Cardiac Autonomic Regulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202509582330608

Enrollment

100

Registered

2025-09-11

Start date

2025-05-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Aerobic exercise

Resistance

combined exercise

standard diabetes care without an exercise regimen.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: o Adults aged 18 years and above diagnosed with T2DM for at least 1 years. o HbA1c levels >6% o Patients not currently engaged in regular structured physical activity. o Ability to provide informed consent.

Exclusion criteria

Exclusion criteria: o Patients on anti-inflammatory medications. o Smokers and individuals with substance use disorders. o Pregnant or breastfeeding women.

Design outcomes

Primary

Measure	Time frame
oNT-proBNP: Indicator of cardiac stress and heart failure risk. oC-reactive protein (CRP): Marker of systemic inflammation. oInterleukin-6 (IL-6): Cytokine involved in inflammation. oTumor Necrosis Factor-alpha (TNF-a): Pro-inflammatory cytokine.	—

Secondary

Measure	Time frame
Heart Rate Variability (HRV) and lung function	—

Countries

Nigeria

Contacts

Public ContactEkundayo Fatai

Senior Physiotherapist

fataidayo.fd@gmail.com+2349031747608

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026