Fertility-female
Conditions
Interventions
Misoprostol administered sublingually at 25mcg every 6hours.
Misoprostol administered vaginally at 25mcg every 6hours to a maximum of 4 doses.
Sponsors
Terna Tivkaa David
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Term pregnancy. 2. A Bishop’s score of less than or equal to 5. 3. A need to terminate pregnancy due to foetal or maternal indications 4. A singleton pregnancy in cephalic presentation with a reassuring foetal heart. 5. The presence of a clinically satisfactory foetus.
Exclusion criteria
Exclusion criteria: 1. Hypersensitivity to prostaglandins or their analogues. 2. Previous caesarean section or other uterine surgeries. 3. Chorioamnionitis 4. Foetal distress and the need for immediate delivery. 5. Women with macrosomia 6. Unexplained vaginal bleeding 7. Multifoetal pregnancy 8. Grand multiparity 9. Asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the proposed study will be the induction-to-delivery interval. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will include the rate of vaginal delivery within 24 hours of induction, mode of delivery, maternal outcomes such as postpartum blood loss, tachysystole (one contraction exceeding two minutes duration), hyperstimulation (6 or more contractions in 10 min), and maternal satisfaction using a validated Likert scale, and neonatal outcomes (Apgar scores, NICU admissions). | — |
Countries
Nigeria
Contacts
Public ContactTunde Olatunji Olubunmi
Consultant Gynaecologist HOD
Outcome results
None listed