Effect of iodophor-impregnated incise drape on skin bacterial recolonization and surgical site infections following open brain and spine surgeries

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202508912216526

Enrollment

Registered

2025-08-14

Start date

2023-11-08

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin bacterial recolonization and surgical site infection following spine surgery Nervous System Diseases

Interventions

3M Iodophor impregnated incised drape

No incised drape

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consenting adult patients aged 18 - 80years, scheduled for cranial or spine surgeries within the limits of the calculated sample size.

Exclusion criteria

Exclusion criteria: • Patients with open traumatic wounds at the operation site • Patients with active infection • Patients requiring re-operation in whom the previous wounds have not healed • Patients with uncontrolled medical risk factors for developing infections, including diabetes mellitus • Active smokers • Patients with allergy to iodine and those who develop allergy following the application of IIID • Patients in whose surgery there was a breach of asepsis • Procedures lasting less than 30 minutes from the completion of skin preparation to the completion of wound closure

Design outcomes

Primary

Measure	Time frame
Bacterial skin recolonization measured as colony forming units.	—

Secondary

Measure	Time frame
Surgical site infection	—

Countries

Nigeria

Contacts

Public ContactChizowa Ezeaku

Senior Registrar

ezeakuchizowa@gmail.com+2348080054944

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026