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YAG Laser Peripheral Iridotomy in Primary Angle Closure

Impact of YAG Laser Peripheral Iridotomy on Anterior Segment in Primary Angle Closure using Optical Coherence Tomography and Corneal Tomography

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202508908830998
Enrollment
30
Registered
2025-08-07
Start date
2024-08-04
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Sponsors

Zagazig University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient aged > 40 years fulfilling the criteria of PACS or PAC: primary angle closure suspect (PACS): characterized by narrow angles by gonioscopy (at least 180°of trabecular meshwork is invisible), but without IOP elevation, glaucomatous damage of the optic nerve, or visual field changes. Primary angle closure (PAC): having the same previous criteria but with elevated IOP and/or peripheral anterior synechia.

Exclusion criteria

Exclusion criteria: 1) Patients with history of previous ocular or refractive surgery, ocular injury, or laser procedure. 2) Patients with concurrent ocular pathology as cataract, diabetic retinopathy, dense corneal opacity, other posterior segment pathology or secondary glaucoma. 3) Patients with chronic angle closure with history of recurrent attacks of acute angle closure with extensive PAS that necessitates surgical intervention. 4) Patients with severe systemic disease and unable to tolerate LPI treatment such as tremors, heart and liver diseases. 5) Patients unable to cooperate for the examination, or unsuitable for gonioscopy like severe uveitis.

Design outcomes

Primary

MeasureTime frame
Measure and compare changes in the anterior chamber parameters in patients with primary angle closure suspect and primary angle closure before and after laser peripheral iridotomy using gonioscopic examination, AS-OCT, and corneal tomography.

Secondary

MeasureTime frame
1- Correlate between the anterior chamber parameters measured by AS-OCT, corneal tomography and gonioscopy. 2- Report changes in intraocular pressure one month and 3 months after LPI in patients with PACS and PAC. 3- Report any complications related to the intervention.

Countries

Egypt

Contacts

Public ContactMarwa Khairy

lecturer of ophthalmology

marwakhairy@medicine.zu.edu.eg+201111801956

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026