Respiratory
Conditions
Interventions
Sponsors
Nadda
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients of both genders admitted in the ward with exacerbation of COPD (moderate exacerbation according to GOLD 2023). 2. Dyspnea with history of baseline dyspnea, expectoration or exposure to biomass fuel exposure or any similar occupational hazards. 3. Current smokers.
Exclusion criteria
Exclusion criteria: 1. Concomitant respiratory disease (e.g., asthma) or associated with a terminal disease (e.g., metastatic cancer). 2. Patients who need intensive care unit (ICU) admission and/or mechanical ventilation. 3. Patients who had taken any mucolytics in the preceding week. 4. Patients with gastro-intestinal bleeding or with risk of bleeding. 5. Pregnant women or breast-feeding mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in the patient’s oxygen status with a target of saturation 88-92%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in clinical status including dyspnea (applying Modified Medical Research Council (mMRC) dyspnea scale), wheezing (presented as percentage of patients), and decrease in time of stay in hospital (period of the exacerbation). | — |
Countries
Egypt
Contacts
Public ContactNadda Badran
Study Coordinator Clinical Pharmacist Ain Shams Universities Hospital
Outcome results
None listed