preeclampsia and eclampsia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All women diagnosed with preeclampsia admitted into the labour ward of ABUTH Zaria who consent to participate in the study. All women diagnosed with eclampsia admitted into the labour ward of ABUTH Zaria who consent to participate in the study.
Exclusion criteria
Exclusion criteria: Pregnancies less than 28 weeks' gestation based on last menstrual period or early USS, admitted into the labour ward. Those who had loading dose of MgSO4 prior to presentation. Those treated with other anticonvulsants prior to presentation Multiple gestation Intrauterine fetal death at presentation. Known allergy to Magnesium sulphate Moribund patients with preeclampsia and eclampsia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence and recurrence of seizures in patients with preeclampsia and eclampsia following administration of the low dose and Pritchard MgSO4 regimen and Pritchard regimen. | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal outcome such as signs of MgSO4 toxicity, mode of delivery, need for rescue dose of MgSO4, ICU admission, maternal complications like visual loss, pulmonary oedema, DIC, HELLP syndrome and acute kidney injury as well as maternal mortality. Neonatal outcome such as APGAR in 1 and 5 minutes, birth weight, need for rescue dose, NICU admission and perinatal mortality | — |
Countries
Nigeria
Contacts
PhD candidate Ahmadu Bello University Zaria