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Age-expanded malaria community case management in Malawi

Assessing the effectiveness of extending malaria community case management (mCCM) to all ages in Neno, Ntchisi and Salima, Malawi: a mixed methods study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202508639314232
Enrollment
7200
Registered
2025-08-01
Start date
2022-01-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria

Interventions

Age expanded malaria community case management.
Standard integrated community case management

Sponsors

Training and Research Unit of Excellence
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria for surveys conducted at baseline (January-February 2022) and endline (January-February 2023) are: - Individuals older than 2 months from one of the 1584 households selected at random - Who spent at least 7 nights in the household during the 2 weeks prior to the survey - With an informed consent signed by the head of the household or representative - In addition, biological samples (Rapid Diagnostic Test for malaria and filter paper) will be obtained from children aged 2 months to 14 years, with written assent provided by individuals 7 to 14 years old. Inclusion criteria for the intervention (community case management of malaria): - Individuals older than 2 months living in the catchment area of one of the 15 health centers in the intervention arm - Without malaria signs of severity (WHO definition)

Exclusion criteria

Exclusion criteria: Exclusion criteria for the intervention (community case management of malaria): - Pregnant women - Aged 2 months or less - With malaria signs of severity (WHO definition)

Design outcomes

Primary

MeasureTime frame
Proportion of individuals two months of age or older, reporting a fever in the previous 2 weeks who were tested for malaria by a CHW or at a health facility by a health worker.

Secondary

MeasureTime frame
Proportion of children <5 years, children 5- 14 years, and those aged 15+ years with febrile illness in the previous 2 weeks who: 1) sought care for that illness; 2) were tested for malaria; and 3) were treated with an appropriate antimalarial if tested positive for malaria;Community-level parasite prevalence in children 2 months to 14 years (<5 and 5 – 14 years) of age as measured by malaria RDT and by serological testing using dried blood spots collected on filter paper.;Proportion of suspected pneumonia and diarrhea in children <5 years who sought care and who received appropriate treatment;Acceptability of the extension to all ages of CCM-malaria, according to community members, CHWs, and health facility providers. This will be assessed through qualitative surveys.;Total costs, resource needs (commodities, workload changes), the cost per patient, and the cost-effectiveness of extending community case management to all ages, as compared to the standard iCCM strategy. This will be measured by economic evaluation.

Countries

Malawi

Contacts

Public ContactKamija Phiri

Professor in Clinical Epidemiology College of Medicine Director TRUE

kamijaphiri@gmail.com+2651871911

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026