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Laparoscopic versus open low anterior resection for rectal cancer

Laparoscopic versus open low anterior resection for rectal cancer

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202508580100870
Enrollment
40
Registered
2025-08-05
Start date
2023-02-14
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Surgery

Interventions

Laparoscopic Low Anterior Resection
Open Low Anterior Resection

Sponsors

Al Azhar University hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients with rectal cancer who were candidates for low anterior resection tumors located in the upper rectum (ten to fifteen centimeters from the anorectal ring), middle rectum (five to ten centimeters from the anorectal ring), and low rectum (0–5 centimeters from the anorectal ring), provided that low rectal tumors had a distal margin of more than one centimeter, with an additional one centimeter of rectum preserved to allow for a stapled anastomosis.

Exclusion criteria

Exclusion criteria: patients with metastatic tumors those presenting with complications like bleeding, obstruction, or perforation. cases with locally advanced tumors cancer invasion into adjacent organs, pregnancy coagulopathy, Patients who weren’t candidates for low anterior resection (LAR), whether open or laparoscopic, but could instead undergo abdominoperineal resection (APR) tumor fixation to bones on digital rectal examination, inadequate distal margin even with intersphincteric dissection, involvement of the external sphincter by the tumor, preoperative fecal incontinence, poor preoperative (or predicted preoperative) sphincter function.

Design outcomes

Primary

MeasureTime frame
analyzing the length of resection safety margins, including both the distal margin and the circumferential resection margin; the number of harvested lymph nodes; the mesorectal excision quality or mesorectal grade; and the patterns and rate of local or distant tumor recurrence throughout the monitoring interval.

Secondary

MeasureTime frame
operative time, gastrointestinal (GIT) recovery, postoperative pain and the corresponding analgesic needs, period of hospitalization, operative morbidity, specific complications, such as postoperative sexual dysfunction; and conversion rate

Countries

Egypt

Contacts

Public ContactAhmad Hasan

Professor of general surgery Faculty of Medicine Al Azhar university Assiut

ahmedmohamedhassanahmed.44@azhar.edu.eg+201002851771

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026