Anaesthesia
Conditions
Interventions
D group dexmedetomidine group
N group nalbuphine
Sponsors
menofia univeristy faculty of medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Adult patients aged 20–70 years undergoing elective FESS in Menoufia university hospitals. ? ASA I-II physical status. ? Informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: ? Patients with a history of opioid dependence or abuse. ? Patients with known allergies to nalbuphine or dexmedetomidine. ? Patients with a history of chronic pain or receiving chronic pain management. ? Patients with a history of psychiatric or neurological disorders. ? Patients with history of previous attack of delirium. ? Patients with cardiac disease. ? Patients with hepatic or renal insufficiency. ? Patients who were pregnant or breastfeeding. ? Patients who required emergency surgery or who were unable to give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparison between Dexmedetomidine and Nalbuphine in prevention of emergence delirium. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes include comparing the effectiveness of Dexmedetomidine and Nalbuphine in postoperative sedation, analgesia, intraoperative hemodynamics, drug related side effects, total dose of nitroglycerine and propranolol needed to reach target controlled hypotensive anesthesia, the length of PACU and hospital stay after surgery. | — |
Countries
Egypt
Contacts
Public ContactTarek Elhennawy
Lecturer of anaesthesiology ICU and pain managment menoufia univerisity
Outcome results
None listed