Repair vs Non-Repair in Tricuspid Regurgitation

Outcomes of Repair Vs Non-Repair of Moderate Functional Tricuspid Valve Regurgitation in Patients Undergoing Mitral Valve Replacement for Severe Stenotic Rheumatic Mitral Valve

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202508544574996

Enrollment

Registered

2025-08-05

Start date

2024-01-09

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System

Interventions

Repair Group

No repair group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Severe rheumatic mitral stenosis + moderate functional TR. Age = 20 years. Planned MVR with LVEF = 50%. No organic TV disease or concomitant surgeries.

Exclusion criteria

Exclusion criteria: Organic tricuspid valve disease (congenital, traumatic, endocarditis, carcinoid) Tricuspid stenosis LVEF < 50% Need for concomitant cardiac procedures Redo operations Other: severe PH, non-rheumatic MV disease, active infection

Design outcomes

Primary

Measure	Time frame
1. Tricuspid regurgitation progression - Method: Echocardiography (grade 0–3)	—

Secondary

Measure	Time frame
Right ventricular function: TAPSE (mm)	—

Countries

Egypt

Contacts

Public ContactAbdelkareem Elias

Assistant Professor of General Surgery

kareemmgerem1235.el@azhar.edu.eg201093959901

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026