Use of sublingual misoprostol and peri-cervical tourniquet in reducing intraoperative blood loss during abdominal myomectomy in Kaduna, Nigeria

Sublingual Misoprostol and Peri-cervical Tourniquet for Reducing Intraoperative Blood Loss at Abdominal Myomectomy in Kaduna, Nigeria: A Randomised Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202507757694585

Enrollment

138

Registered

2025-07-10

Start date

2025-07-14

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Placebo and Pericervical tourniquet

Misoprostol and Pericervical tourniquet

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Reproductive-age women (15 - 49 years). Diagnosis of uterine fibroids made through transabdominal or transvaginal ultrasound scans.

Exclusion criteria

Exclusion criteria: Known hypersensitivity to prostaglandins. Had received gonadotropin-releasing hormone analogues or ulipristal acetate within 3 months before surgery. Known bleeding disorder. Known medical conditions like mitral stenosis, sickle cell disease, glaucoma and severe asthma.

Design outcomes

Primary

Measure	Time frame
The mean intraoperative blood loss in the study and control group	—

Secondary

Measure	Time frame
Mean change between the preoperative and postoperative hemoglobin concentration in study and control groups.;Proportion of perioperative blood transfusion in the study and control group.;Incidence of drug side effects in study and control group.	—

Countries

Nigeria

Contacts

Public ContactHafsat Abdullahi Maikudi

Resident Doctor at Ahmadu Bello University Teaching Hospital

hafsahmaikudi@gmail.com+2348036948593

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026