Circulatory System Kidney Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adults aged =18 years CKD patients (eGFR 15–60 mL/min/1.73 m²) Undergoing elective coronary angiography At least one risk factor for CA-AKI (e.g., age >75, diabetes, hypertension, CHF NYHA >II, LVEF =35%, history of pulmonary edema)
Exclusion criteria
Exclusion criteria: Patients on dialysis Prior kidney or heart transplant Recent contrast exposure or acute infection Acute decompensated heart failure Pregnancy or lactation Active malignancy or life expectancy <1 year Recent nephrotoxic drug use Scheduled for cardiac surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Incidence of CA-AKI within 72 hours post-procedure (defined as =25% or =0.5 mg/dL rise in serum creatinine from baseline). | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospital stay Change in serum creatinine (SCr) Need for dialysis Adverse events (infection, pulmonary edema) | — |
Countries
Egypt
Contacts
Lecturer of internal medicine and nephrology Tanta University