Pregnancy and Childbirth
Conditions
Interventions
parenteral oxytocin plus 400mcg sublingual misoprostol
water for injections plus 400mcg sublingual misoprostol
parenteral 10IU oxytocin plus sublingual two tablets of placebo
Sponsors
self
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. All consenting pregnant women in the active phase of labour. 2. Estimated gestational age at term (37-42 weeks) at time of delivery.
Exclusion criteria
Exclusion criteria: 1. Women with intrapartum anaemia (Hb <8g/dl) 2. Antepartum haemorrhage 3. Pre-existing history of maternal haemorrhagic disease. 4. Recent use of antiplatelet drugs. 5. Hypersensitivity to prostaglandins 6. Women scheduled for elective cesarean section who present in the active phase of labour.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes will be the mean blood loss during the third stage of labour | — |
Secondary
| Measure | Time frame |
|---|---|
| This will comprise the duration of the third stage of labour, the occurrence of primary postpartum hemorrhage, significant differences between intrapartum and postpartum haemoglobin levels, retained placenta, severe postpartum hemorrhage, the need for additional uterotonics to treat life-threatening hemorrhage, blood transfusion, and medication side-effects. | — |
Countries
Nigeria
Contacts
Public Contactabiodun Adeniran
co investigator
Outcome results
None listed