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Evaluation of the effect of tranexamic acid injection on the estimated blood loss among anemic women undergoing delivery

Evaluation of the effect of tranexamic acid injection on the estimated blood loss among anemic women undergoing delivery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202506916530208
Enrollment
540
Registered
2025-06-20
Start date
2025-06-30
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

Sponsors

suez canal university
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: a) women aged 18-45 years, b) women delivering vaginally or by cesarean section, c) women diagnosed with anemia (Hb < 10.5 g/dl) d) singleton pregnancy with cephalic presentation, e) BMI < 40kg/m2,

Exclusion criteria

Exclusion criteria: a) participants refusing to participate in the study, b) anemia due to blood disease as thalassemia and sickle cell anemia, c) women on anticoagulant therapy, d) preterm birth, e) allergy to TXA, f) abnormal placentation as placenta previa- accreta spectrum -defined as abnormal implantation of the placenta or invasion to the lower uterine segment, g) placental abruption, h) pregnancy-related complications as severe preeclampsia,

Design outcomes

Primary

MeasureTime frame
the amount of peripartum blood loss in both groups

Secondary

MeasureTime frame
the incidence of PPH defined as blood loss = 1000 ml for women having CS and = 500 ml for women having vaginal delivery, need for surgical intervention (hysterectomy, laparotomy, embolization, uterine compression sutures, and arterial ligation) in cases with PPH, and need for blood transfusion.

Countries

Egypt

Contacts

Public Contactislam Albiadi

Suez Canal University

eslamalbayadi@gmail.com+2001223666764

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026