Nurse-Led Insulin Protocol for Managing High Blood Sugar in Critically Ill ICU Patients

Nurse-Led Insulin Protocol Efficacy for Control of Hyperglycemia in Critically Ill Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202506863203683

Enrollment

Registered

2025-06-04

Start date

2024-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Nurse Led Insulin Infusion Protocol

Standard Physician directed insulin management

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adults aged 18 to 60 years Admitted to the Intensive Care Unit (ICU) of Fayoum University Hospital Diagnosed with hyperglycemia (defined as blood glucose =150 mg/dL) Able to provide informed consent personally or via a legally authorized representative

Exclusion criteria

Exclusion criteria: Patients diagnosed with Diabetic Ketoacidosis (DKA) Patients diagnosed with Hyperglycemic Hyperosmolar State (HHS) Patients with critical conditions requiring alternative insulin management protocols Patients outside the age range of 18–60 years Patients or their representatives unable or unwilling to provide informed consent

Design outcomes

Primary

Measure	Time frame
Time to Achieve Target Blood Glucose Levels Description: Number of days taken to reach blood glucose levels within the target range (110–149 mg/dL) Time Frame: Up to 7 days from ICU admission Measurement Method: Blood glucose monitoring records Mean Blood Glucose Levels Over Time Description: Comparison of average blood glucose levels across five measurement points post-baseline Time Frame: Within the ICU stay (1–7 days) Measurement Method: Capillary blood glucose measurements using glucometer Length of ICU Stay Description: Total number of days patients remained in the ICU Time Frame: From ICU admission to discharge Measurement Method: ICU admission and discharge records	—

Measure

Time frame

Time to Achieve Target Blood Glucose Levels Description: Number of days taken to reach blood glucose levels within the target range (110–149 mg/dL) Time Frame: Up to 7 days from ICU admission Measurement Method: Blood glucose monitoring records Mean Blood Glucose Levels Over Time Description: Comparison of average blood glucose levels across five measurement points post-baseline Time Frame: Within the ICU stay (1–7 days) Measurement Method: Capillary blood glucose measurements using glucometer Length of ICU Stay Description: Total number of days patients remained in the ICU Time Frame: From ICU admission to discharge Measurement Method: ICU admission and discharge records

—

Secondary

Measure	Time frame
Frequency of Blood Glucose Monitoring Description: Number of blood glucose readings taken during ICU stay Time Frame: During entire ICU admission Measurement Method: Nursing records/logs of glucose monitoring Protocol Adherence Rate Description: Percentage of adherence to the nurse-led insulin protocol steps Time Frame: During intervention period in ICU Measurement Method: Protocol adherence checklists/audit forms	—

Measure

Time frame

Frequency of Blood Glucose Monitoring Description: Number of blood glucose readings taken during ICU stay Time Frame: During entire ICU admission Measurement Method: Nursing records/logs of glucose monitoring Protocol Adherence Rate Description: Percentage of adherence to the nurse-led insulin protocol steps Time Frame: During intervention period in ICU Measurement Method: Protocol adherence checklists/audit forms

—

Countries

Egypt

Contacts

Public ContactSahar Hassanein

Professor of pediatric medicine

saharhassanein@med.asu.edu.eg012776299

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026