Anaesthesia
Conditions
Sponsors
Mona Ismail Mohamed
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Male and female patients aging from 20 years to 60 years old. • Body Mass Index (BMI) 30-40 kg/m2 • ASA II physical status patients scheduled for elective laparoscopic cholecystectomy.
Exclusion criteria
Exclusion criteria: • Patient refusal. • ASA physical status classes III and IV. • Anticipated difficult intubation. • Hypersensitivity to any drugs used in this study. • Inability to remove the endotracheal tube in the operating room. • Conversion to laparotomy. • Severe obstructive pulmonary disease (defined as pulmonary function test done by spirometry where the calculation of FEV1/FVC < 70%).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to assess the impact of two ventilatory strategies, volume versus pressure controlled ventilation on the arterial to end tidal carbon dioxide gradient P (a ET) CO2 in patients undergoing laparoscopic cholecystectomy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include; the effects on alveolar to arterial oxygen gradient P (A a)O2, peak airway pressure (Paw), dynamic compliance (Cdyn) and hemodynamic variables (heart rate and mean arterial blood pressure). | — |
Countries
Egypt
Contacts
Public ContactAmal Hamed Rabea
assistant professor of anesthesia and intensive care unite
Outcome results
None listed