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The effect of inhaled salbutamol and ipratropium bromide on improving the outcomes of transient tachypnea of newborn: clinical trial

The effect of inhaled salbutamol and ipratropium bromide on improving the outcomes of transient tachypnea of newborn: clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202506603201609
Enrollment
87
Registered
2025-06-04
Start date
2022-10-25
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics

Interventions

control group
study group 1 ipratropium bromide
study group 2 salbutamol

Sponsors

suez canal university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All neonates diagnosed with TTN based on clinical and radiological data gestational age from 38-to-42 weeks, cesarean or vaginal deliveries, both genders, incidence of tachypnea (respiratory rate > 60) within the first 6 h of birth and chest X-Ray consistent with retained fluid: congestion, perihilar streaking, fluid in the interlobar fissure.

Exclusion criteria

Exclusion criteria: Neonates with heart rate above 180 beats/minute, cardiac arrhythmias, neonates with congenital malformation, perinatal asphyxia, confirmed systemic infection (positive blood culture), meconium aspiration, respiratory distress syndrome (based on the radiographs), intrauterine growth retardation, history of fetal distress, pneumonitis, congenital heart disease, disseminated intravascular coagulation (DIC), multi-organ failure, hypoxemia, polycythemia .

Design outcomes

Primary

MeasureTime frame
the efficacy and safety of salbutamol and ipratropium bromide in management of TTN

Secondary

MeasureTime frame
drug related side effects

Countries

Egypt

Contacts

Public Contactomima taha

suez canal university faculty of medicine

omimatharwat@yahoo.com01223423685

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026