Malaria
Conditions
Interventions
Seasonal timed RTSS booster dose delivered via routine immunisation clinics
Age based RTSS booster dose delivered via routine immunisation clinics
Sponsors
University Of Sciences Techniques and Technologies de Bamako USTTB
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Residence of the study child’s family in the trial area with an intention to stay in the trial area for the duration of the trial. Age 0-5 months. Provision of informed consent for their child to join the trial from the parents or guardians.
Exclusion criteria
Exclusion criteria: Prior receipt of a malaria vaccine or other experimental malaria intervention such as a monoclonal antibody. Illness which in the opinion of the investigators would not warrant inclusion of a child in a clinical trial, for example severe malnutrition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coverage with the booster dose of the RTS,S vaccine.;The incidence of clinical malaria, detected through passive case detection at a clinic or hospital and diagnosed by RDT or a blood smear, during the period from 5 to 36 months of age. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital admissions due to malaria and all other causes excluding injuries and elective surgery during the period from 5 to 36 months of age;Death due to malaria and all other cause excluding injuries and elective surgery during the period from 5 to 36 months of age;Coverage of SMC, ITN use and other EPI vaccines;Prevalence of malaria parasite and anaemia at the end of the transmission season in year 2 (post-booster 1) and year 3 (post booster 2) of the trial | — |
Countries
Guinea
Contacts
Public ContactLuca Meesters
Project Manager
Outcome results
None listed