Nutritional, Metabolic, Endocrine
Conditions
Interventions
Experimental Group
Early time restricted eating and late training
Late training
Early timed restricted eating
Early training
Sponsors
Endocrinology department of Hadi Chaker University Hospital
Research Laboratory Molecular Bases of Human Pathology LR19ES13 Faculty of Medicine University of Sfax Tunisia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: * Persons diagnosed with type 2 diabetes, 25-65 years of age *BMI: = 26kg/cm2 *Sedentary, able to exercise Physical *Stable weight in the past 6 months * Agree to eat meals during specific hours of the day *On oral antidiabetic drugs *Willing and able to perform laboratory tests on specific dates during the study *HbA1C 10%(<86 mmol.mol-1 )
Exclusion criteria
Exclusion criteria: *Eating disorders *Persons who smoke and are under insulin therapy *Pregnant women, those who breastfeed within 24 weeks of starting the study, as well as those with known cardiovascular problems. *Significant and unstable medical conditions over the past year: Neurological (migraines, convulsions, stroke). *Persons taking drugs that could influence muscle size and strength, such as testosterone and growth hormone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Body composition - Biochemical reponses (inflammation, glucose, lipid profile, thyroid profile, standard profile, hormonal profile, hepatic profile, glycolytique profile , oxidative stress) - cardiovascular function - mood state (pain, anxiety, depression, fatigue), physical performances :6MWT, Squat Jump and Counter Movement Jump ,Cardiorespiratory endurance, Grip strength, test (1RM) ,postural stability (force plateform), quality of life(Questionnaire SF36), endothelial function, Hand grip, chair test (Lower-extremity muscle strength),pulmonair function,cognitive function, we will evaluate oxygenated and deoxygenated hemoglobin muscle (O2Hb and HHb) using near-infrared spectroscopy (NIRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality,( actimetry , self-reported daily evaluation of sleep , and the completion of the Pittsburgh Sleep Quality Index (PSQI) questionnairy) cognitives respenses ,A heart rate monitor, quality of life(Questionnairy SF36)-Chronotype(Questionnairy),Questionnaire caen , Questionnaire (EDE-Q), Hospital Anxiety and Depression Scale (HADS)) , Hunger and Satiety Visual Analogue Scales (VAS),Eating Attitudes Test (EAT 26). | — |
Countries
Tunisia
Contacts
Public ContactSonda ;Dalenda Jallouli;Iben Elwefi
Doctor in biological sciences of sports and physical activities. Research laboratory Evaluation and Management of Musculoskeletal System Pathologies LR20ES09 Faculty of Medicine University of Sfax;Research Laboratory Molecular Bases of Human Pathology LR19ES13 Faculty of Medicine University of Sfax Tunisia
Outcome results
None listed