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Pain-relief after Caesarean section: comparing an opioid-free medicine plan with the usual opioid-based plan for new mothers in Yenagoa.

Opioid versus non-opioid multimodal analgesia for post-caesarean pain: a randomized controlled trial at federal medical centre yenagoa

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202505501883069
Enrollment
120
Registered
2025-05-27
Start date
2025-06-02
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain following Caesarean section

Interventions

Non opioid group
opioid based group

Sponsors

Dr. Benson Azibato Benjamin
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Pregnant women scheduled for either elective or emergency caesarean section and were not affected by the exclusion criteria. 2. Pregnant women who will have elective or emergency caesarean section under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Pregnant women with history of abuse of opioids. 2. Patients with hypersensitivity to pentazocine, paracetamol or diclofenac. 3. Cardio-pulmonary depression. 4. History of active peptic ulcer disease, chronic liver or renal disease. 5. Sickle cell disease. 6. Patients on magnesium sulphate.

Design outcomes

Primary

MeasureTime frame
Postoperative pain scores in both groups.

Secondary

MeasureTime frame
1. Need for rescue analgesia in both groups. 2. Time (in minutes) to first request for analgesic in both groups. 3. Patient satisfaction with pain relief in both groups. 4. Time to return of bowel sounds in both groups. 5. Time to commencement of ambulation in both groups. 6. Frequency of occurrence of side-effects in both groups.

Countries

Nigeria

Contacts

Public ContactNuvie Oyeyemi

Consultant obstetricianGynaecologist

nuviyemi@yahoo.com+2348035488675

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026