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Comparative evaluation of the effect of two different types of calcium hydroxide on periapical granuloma - A randomized comparative trial

Comparative evaluation of the effect of two different types of calcium hydroxide on periapical granuloma - A randomized comparative trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202504838489580
Enrollment
128
Registered
2025-04-30
Start date
2018-08-09
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

calasept
Calcium hydroxide mixed with normal saline chair side mix

Sponsors

Ololade Akinyemi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients within the age range of 18 – 50 years. Patients that have consented to participate. Patients willing to comply with appointments. Patients with matured non-vital anterior (central incisors, lateral incisors and canines) teeth. Anterior teeth with periapical radiolucencies with well circumscribed unilateral radiolucency without sclerotic margins. Anterior teeth with periapical radiolucencies with or without caries. Anterior teeth that have not undergone root canal treatment. Anterior teeth that have not had previous surgical intervention. Anterior teeth with apical radiolucent lesions of periapical index (PAI) score of 4 and above. Anterior teeth with periapical radiolucent lesions of horizontal diameter = 5mm

Exclusion criteria

Exclusion criteria: Patients with history of uncontrolled diabetes Patients with history of uncontrolled hypertension Immunosuppressed patients Inaccessibility to the apical region due to pulpal calcification and pulp stones Dilacerated roots Patients with unrestorable teeth. Teeth with chronic periodontitis. Patients who used antibiotics in the last 2 weeks. Refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
Lesion size reduction in millimetres (mm) using radiographs.

Secondary

MeasureTime frame
Periapical index score changes overtime

Countries

Nigeria

Contacts

Public ContactOlolade Akinyemi

Consultant

ololadeakinyemi@gmail.com+2348036006712

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026