Respiratory
Conditions
Interventions
Diaphragmatic tissue Doppler examination after passing 30 minutes of spontaneous breathing trial
Sponsors
Ashraf Amin Mohammed Hussein
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: o Age 18 - 65 years o Invasive mechanical ventilation > 48 hours o Patients meet the readiness criteria of weaning include: • The cause of respiratory failure should be resolved or significantly improved • Respiratory rate =10 and =30 breaths per min • Adequate oxygenation o SpO2 > 90% o FiO2 7.30. • Hemodynamic stability with no dynamic changes of myocardial ischemia or hypotension (no or little vasopressors). • Minimal respiratory secretions, intact cough reflex and GCS >9
Exclusion criteria
Exclusion criteria: • Age 65 years • Pregnancy • Neuromuscular diseases • Known diaphragmatic paralysis, surgery or trauma • Fractured ribs, flail chest, thoracostomy • Cachectic patients and patients with malignancy • Spinal trauma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effectiveness of diaphragmatic peak contraction velocity (d-PCV) as a measurable variable of dTDI in predicting weaning outcomes in these patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess other dTDI variables, including contraction acceleration (d-AC), peak relaxation velocity (d-PRV), and relaxation acceleration (d-AR), and to assess the correlation between dTDI variables and factors such as mechanical ventilation days, ICU length of stay, and 7-day mortality. | — |
Countries
Egypt
Contacts
Public ContactAbd Alrahman;Ashraf Ahmed;Eskandr
Associate Prof. Anesthesiology intensive Care and Pain Faculty of Medicine Menoufia University;Prof. of Anesthesiology Intensive Care and Pain Faculty of Medicine Menoufina University
Outcome results
None listed