Digestive System Nutritional, Metabolic, Endocrine Surgery Paediatrics
Conditions
Interventions
GLP1 and GIP changes after sleeve gastrectomy and after weight regain in adolescents
Sponsors
none
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Adolescents aged 10–19 years with morbid obesity who underwent laparoscopic sleeve gastrectomy (LSG) in the form of antral resection [the first staple firing started 2 cm from the gastro duodenal junction (pyloric ring)]
Exclusion criteria
Exclusion criteria: - patients aged 19 years - those who underwent laparoscopic sleeve gastrectomy with antral preservation [the first staple firing started more than 2 cm from the pyloric ring] - alternative bariatric procedures as Roux-en-Y gastric bypass (RYGB) or laparoscopic adjustable gastric banding (LAGB) during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome evaluated longitudinal changes in fasting/postprandial GLP-1 and GIP levels post-LSG and their correlation with weight regain over five years. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included reductions in BMI, %EWL, and HbA1c; partial weight regain post-year 3; and comorbidity resolution. | — |
Countries
Egypt
Contacts
Public ContactAhmed Elhaddad
Professor of pediatric surgery Department of general surgery Faculty of Medicine Tanta University Tanta Egypt
Outcome results
None listed