Anaesthesia
Conditions
Interventions
Nalbuphine plus Bupivacaine in Bilateral ESPB
Fentanyl plus Bupivacaine in Bilateral ESPB
Sponsors
Cairo University Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women aged 20 to 35 years ASA physical status II BMI between 18–30 kg/m² Scheduled for elective cesarean section under spinal anesthesia
Exclusion criteria
Exclusion criteria: Patient refusal Severe cardiac diseases (e.g., rheumatic valve disease, cardiomyopathy) Local infection at injection site Coagulopathy Contraindications to spinal anesthesia Known allergy to any of the study drugs Prolonged or complicated cesarean section lasting >45 minutes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first request for rescue analgesia in hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain score (NRS 0–10, at rest and with coughing);Total nalbuphine consumption (mg) over 24 hours;Hemodynamic parameters (Mean arterial pressure and Heart rate);Patient satisfaction (5-point Likert scale);Adverse effects (PONV, respiratory depression, pruritus, pneumothorax, hemodynamic instability, local anesthetic toxicity) | — |
Countries
Egypt
Contacts
Public ContactManar Mahmoud
Department of Anesthesia Surgical ICU and Pain Management Faculty of Medicine Cairo University
Outcome results
None listed