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Efficacy of two brands of mebendazole (500mg) in the treatment of Ascaris lumbricoides and hookworm infection among school-aged children, south Gonar zone Northwest Ethiopia

Efficacy of two brands of mebendazole (500mg) in the treatment of Ascaris lumbricoides and hookworm infection among school-aged children, south Gonar zone Northwest Ethiopia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202503808932606
Enrollment
200
Registered
2025-03-27
Start date
2021-01-12
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infection/Infestation

Interventions

X worm mebendazole
Vermox Mebendazole

Sponsors

Uiversity of Gonder
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Study participants whose age ranges from 6-14 years Individuals confirmed with Ascaris lumbricoides and hookworm mono-infection

Exclusion criteria

Exclusion criteria: Presence or history of known major systemic or chronic illnesses (based on physical examination and Medical history and student interview) Received anthelminthic treatment or metronidazole within the past four weeks. Attending other clinical trials during the study periods. Experienced a severe allergic reaction to mebendazole(interviewing study participants), Infected with other parasitic infections Diarrheic children Children vomited within 4 hours after the drug taken Unable to give sufficient sample

Design outcomes

Primary

MeasureTime frame
Cure rate or CR. CR means the proportion of individual hosts positive for parasites who become parasitologically negative after treatment

Secondary

MeasureTime frame
Arithmetic mean of Feacal Egg Reduction Rate OR ERR. ERR is the arithmetic mean egg count at baseline of the treatment group minus mean egg count at the end of treatment period divided by the mean egg count at the baseline and express it in percent.

Countries

Ethiopia

Contacts

Public ContactAyalew Jejaw

Lecturer

ayalewjejaw@gmail.com+251985024932

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026