Injury, Occupational Diseases, Poisoning
Conditions
Interventions
Conventional treatment
Sponsors
Tanta University Hospitals
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? adult patients (aged 18 years or older) ? symptomatic acute ALP poisoning ? admitted within 12 hours of exposure
Exclusion criteria
Exclusion criteria: ? Patients aged less than 18 years old ? Patients died shortly after admission ? Patients with pre-existing chronic diseases (e.g. cardiovascular disease, renal or hepatic failure, diabetes, and chronic pulmonary disease) ? Patients with combined drug or chemical compound ingestion in addition to ALP ? Patients who received any medical intervention before admission ? Pregnant and lactating women ? Patients with known hypersensitivity to NAC or using it for other diseases ? Patients receiving chemotherapeutic drugs or warfarin treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In-hospital mortality | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation ;Duration of hospital stay;Troponin I;Incidence of adverse events.;Time to recovery from critical symptoms (e.g., return of normal GCS, resolution of acidosis).;Total antioxidant capacity;Malondialdehyde levels;Hemodynamic stability (blood pressure);arterial blood gases | — |
Countries
Egypt
Contacts
Public ContactMona Ghonem
assistant professor of forensic medicine and clinical toxicology
Outcome results
None listed