Comparison of effectiveness of dexamethasone and ondansetron in preventing spinal headache following cesarean section in Federal Teaching Hospital Owerri

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202503701455932

Enrollment

144

Registered

2025-03-19

Start date

2025-03-20

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Anaesthesia

Interventions

Dexamethasone

Ondansetron

Sterile water

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All pregnant women for elective cesarean section between 28 and 42 completed weeks that are willing to participate in the trial

Exclusion criteria

Exclusion criteria: Women with history of allergy to ondansetron or dexamethasone will be excluded from the study. Those with past history of chronic headache or recent onset of acute headache. Hypertensive disorders in pregnancy Previous brain or neurological surgery

Design outcomes

Primary

Measure	Time frame
Occurrence and severity of postdural puncture headache	—

Secondary

Measure	Time frame
Nausea and vomiting	—

Countries

Nigeria

Contacts

Public ContactAdanna Egwim

Medical Doctor

adanna.egwim@npmcn.edu.ng+2348038747375

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026