Anaesthesia
Conditions
Interventions
Endo tracheal dexmedetomidine group
Endo tracheal lidocaine group
Normal saline endo tracheal injection
Sponsors
Cairo University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Male and female patients 18 to 65 years old ASA ? or ?? undergoing elective abdomino-plasty surgery
Exclusion criteria
Exclusion criteria: Allergy to dexmedetomidine or lidocaine History of cardiac disease as heart block, sick sinus syndrome and coronary heart disease History of respiratory disease as bronchial asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, pneumonia, and lung cancer Renal insufficiency Hepatic insufficiency Uncontrolled hypertensive patients Significant obesity (BMI > 40) Long-term use of sedative hypnotics Refusal of the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Smoothness of extubation assessed using a 4-point extubation quality scale;Hemodynamic parameters (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure) during extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time: Time from discontinuation of isoflurane to tracheal extubation;Degree of sedation post-extubation: Measured using the Ramsay Sedation Scale;Incidence of post-extubation complications: Including laryngospasm, bronchospasm, or desaturation | — |
Countries
Egypt
Contacts
Public ContactDina Othman
Department of Anesthesia Surgical ICU and Pain Management Faculty of Medicine Cairo University
Outcome results
None listed